CLEMSON, S.C. (AP) -- Clemson players are well aware of last week's big upset of Mississippi and they are determined not to be the next major team to fall to one of their little brothers in Division I.

The Tigers are preparing for Presbyterian this week, an obvious mismatch on many levels. The Blue Hose have lost 15 in a row and play in the Football Championship Subdivision. Clemson has never lost in 23 games against FCS teams.

But Tigers offensive lineman Chris Hairston says everyone on the team better take Saturday's game seriously, especially after seeing Ole Miss lose 49-48 in double overtime to FCS team Jacksonville State.

Hairston says the Blue Hose have good players who would love to embarrass guys that got to play for a higher division team like Clemson.

(Copyright 2010 by The Associated Press. All Rights Reserved.)